猪肺炎支原体感染早期诱导猪呼吸道产生多种特异性IgA抗体分泌规律研究

doi:10.11843/j.issn.0366-6964.2013.05.014

Abstract

Abstract:

This experiment was conducted to study the initial secretive features of specific IgA antibodies against P36, P46 and P97R1 proteins produced in the respiratory tract after the pigs were affected with Mycoplasma hyopneumoniae (Mhp). Total seven pigs were infected with Mhp strain. The nasal swabs were collected at the 1st, 2nd, 4th, 6th, 8th, 12th, 16th and 21st day post inoculation (dpi) to detect specific IgA titers against P36, P46, P97R1 proteins by the three established indirect enzyme-linked immunosorbent assays (ELISA). The IgA titers were normalized by the total protein concentration of nasal swab samples. The results showed that levels of three sorts of specific IgA start to rise at the 6th dpi and reach the peak at the 12th dpi. The high levels could be kept until to end of assay (the 21st dpi). The secretive features of three specific IgA antibodies were consistent as well as the secretive amounts on the same day (P>0.05). In conclusion, P36, P46 and P97R1 proteins could induce the specific IgA antibody in the respiratory tract during the early stage of infection with the same trends and secretive amounts.

CLC Number:

S852.62
S855

YAO Jing-ting, FENG Zhi-xin, LIU Mao-jun, XIONG Qi-yan, BAI Fang-fang, HUA Li-zhong, WANG Hai-yan, GAN Yuan, WEI Yan-na, SHAO Guo-qing. Research on the Initial Secretive Feature of Specific IgA Antibody in Respiratory Tract of Pigs Infected with Mycoplasma hyopneumoniae[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2013, 44(5): 767-771.

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Research on the Initial Secretive Feature of Specific IgA Antibody in Respiratory Tract of Pigs Infected with Mycoplasma hyopneumoniae

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